Name:Li Xu
Address:School of Life Sciences,

University of Science and Technology of China
Tel:86 0551 63607334
E-mail:sachem@ustc.edu.cn
Home page:https://www.researchgate.net/profile/Xu_Li4
EDUCATION AND RESEARCH EXPERIENCE
1997.09 - 2001.07Bachelor of Biology Science

University of Science and Technology of China,Hefei
2001.09 - 2007.07Ph. D. of Structural Biology

University of Science and Technology of China,Hefei
2003.09 - 2014.05Lecturer of School of Life Sciences, USTC
2014.06 -Associate Professor of School of Life Sciences, USTC
RESEARCH INTERESTS
1.The structural mechanism and biological function of protein-nucleic acid complex interactions;
2.The Structural basis for the pathogenesis of pathogenic bacteria;
3.The discovery, improvements and industrial applications of the novel enzymes.
SELECTED PUBLICATIONS
1.Crystal structure of DnaT(84-153)-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode. NUCLEIC ACIDS RESEARCH 42(14) 9470-9483 2014.08 Corresponding Author (7/7);
2.Structural and Functional Basis of Difructose Anhydride III Hydrolase, Which Sequentially Converts Inulin Using the Same Catalytic Residue. ACS CATALYSIS 8 10683-10697 2018.11 Corresponding Author (5/6);
3.Crystal structure of tRNA m(1)G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate NUCLEIC ACIDS RESEARCH 42 509-525 2014.01 Corresponding Author (13/14);
4.Caulobacter crescentus beta sliding clamp employs a noncanonical regulatory model of DNA replication. FEBS JOURNAL 15138 2019.11 Corresponding Author (13/14);
5.Crystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation. JOURNAL OF BIOLOGICAL CHEMISTRY 2;288(31):22636-49 2013.08 Corresponding Author (8/8);
6.Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly ACTA CRYSTALLOGR D 69 2412-2419 2013.12 Corresponding Author (5/5);
7.Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricin SCIENTIFIC REPORTS 6 37803 2016.11 Corresponding Author (6/6);
8.Structure of Rot, a global regulator of virulence genes in Staphylococcus aureus ACTA CRYSTALLOGR D 70 2467-2476 2014.09 Corresponding Author (7/7);
9.Structural analysis of shu proteins reveals a DNA binding role essential for resisting damage. JOURNAL OF BIOLOGICAL CHEMISTRY 287(24) 20231-20239 2012.06 Co-first Author (2/7);
10.Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins BIOCHEMICAL JOURNAL 470 105-114 2015.08  Corresponding Author (6/8).

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