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Copper-catalyzed propargylation of diborylmethane
Chemical Communications 53(25):3551-3554 Mar 2017

Li, Feng; Zhang, Zhen-Qi; Lu, Xi; Xiao, Bin; Fu, Yao

A Cu/PPh3-catalyzed propargylic substitution reaction of diborylmethane is reported. Different substituted propargyl electrophiles can be employed in this reaction, and various synthetic valuable functional groups can be tolerated. Di-deuterated diborylmethane can also be used under these conditions and generates α-deuterated alkylboronic esters in good yield.

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