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YANG Zhenye, Professor, Young Thousand Talents Program Bio-X Interdisciplinary Sciences
Name:  Zhenye Yang (杨振业)
Address: School of Life Sciences
University of Science & Technology of China,
443 Huangshan Street, Hefei City, Anhui 230027
Tel: 0551-63600613
E-mail: zhenye@ustc.edu.cn
 
EDUCATION AND RESEARCH EXPERIENCE
2013- Professor, School of Life Sciences, University of Science & Technology of China
2010-2013 Research Fellow, National Cancer Institute, NIH
2005-2010 Research Scientist, Wadsworth Center, New York State Department of Health
1999-2005 Ph.D, Shanghai Institute of Biochemistry and Cell Biology, ChineseAcademy of Sciences
1995-1999 B.S., School of Life Science, Shanghai Jiao Tong University
 
RESEARCH INTERESTS
1) Function of cell division regulators in tumor progression
2) Mechanism of anti-mitotic therapeutics and combination therapy
3) Roles of inflammation in anti-mitotic and target chemotherapy
 
CURRENT RESEARCH PROJECTS
青年千人计划,国家重大基础研究计划,自然科学基金委项目
 
REPRESENTATIVE PUBLICATIONS
1) Wan Y, Yang, Z, Guo J, Zhang Q, Zeng L, Song W, Xiao Y and Zhu X. 2012. Misfolded Gbeta2 is recruited to cytoplasmic dynein by Nudel for efficient clearance. Cell Res.doi: 10.1038/cr.2012.47
2) Yang, Z., Kenny A., Brito D. and Rieder C. 2009. Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments. J Cell Biol.186: 675-684.
3) Yang, Z., Loncarek J., Khodjakov A. and Rieder C. 2008. Extra centrosomes and/or chromosomes prolong mitosis in human cells. Nat .Cell Biol. 10: 748-751.
4) Brito D.*, Yang, Z.* and Rieder C. 2008. Microtubules do not promote mitotic slippage when the Spindle Assembly Checkpoint cannot be satisfied. J Cell Biol.182(4):623-9. (* Co-first author)
5) Yang, Z., Tulu S., Wadsworth P. and Rieder C. 2007. Kinetochore Dynein is Required for Normal Chromosome Motion and Congression Independent of the Spindle Checkpoint. Curr. Biol.17(11): 973-80.
6) Yang, Z., Guo J., Chen Q., Du J., Ding C., and Zhu X.2005. Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death. Mol. Cell. Biol. 25: 4062-4074.
7) Yang, Z., Guo J., Li N., Qian M., Wang S, and. Zhu X. 2003. Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transport. Cell Res. 13:275-83.

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