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WU Qingfa, Professor Bio-X Interdisciplinary Sciences
Name:  Qingfa Wu (吴清发)
Address: School of Life Sciences, University of Science and Technology of China, 230026 Hefei, P. R. China
Tel: 86-551-63607631
Fax: 86-551-63606525
E-mail: wuqf@ustc.edu.cn
Homepage:   http://staff.ustc.edu.cn/~wuqf
 
EDUCATION AND RESEARCH EXPERIENCE
吴清发,教授,博士生导师。2003年获得中国科学院遗传发育所博士学位。2011年10月到2012年8月,作为交流博士生,在丹麦哥本哈根大学Panum医学院从事人类疾病基因的定位克隆工作。2004年4月到2006年10月,在美国西北大学从事博士后研究, 主要进行人造血干细胞转录谱的研究工作。 2006年10月-2010年10月,在美国加州大学河滨分校从事病毒-宿主相互作用机制的研究。2010年10月起任中国科学技术大学生命科学学院教授。
 
RESEARCH INTERESTS
1) 生物信息学工具的开发和应用
2) 病毒--宿主互作机制
 
详细情况见实验室网页:http://staff.ustc.edu.cn/~wuqf
 
REPRESENTATIVE PUBLICATIONS
1) Zhang Z, Qi S, Tang N, Zhang X, Chen S, Zhu P, Ma L, Cheng J, Xu Y,Lu M, Wang H, Ding S, Li S&,Wu Q& . Discovery of replicating circular RNAs by RNA-seq and computational algorithms. PLOS Pathogens.2014, 10(12): e1004553. (& Corresponding author
2) Wu Q#, Wang Y#, Cao M, Pantaleo V, Burgyan J, Li WX, Ding SW. Homology independent discovery of replicating pathogenic circular RNAs by deep sequencing and a new computational algorithm. Proc Natl Acad Sci U S A. 2012 Mar 6; 109(10):3938-43.
3) Han YH#, Luo YJ#, Wu Q#&, Jovel J, Wang XH, Aliyari R, Han C, Li WX, Ding SW. RNA-based immunity terminates viral infection in adult Drosophila in the absence of viral suppression of RNA interference: characterization of viral small interfering RNA populations in wild-type and mutant flies. J Virol. 2011 Dec;85(24):13153-63. (# Co-first author,& Co-corresponding author)
4) Wu Q, Wang X, Ding SW.Viral suppressors of RNA-based viral immunity: host targets. Cell Host Microbe. 2010 Jul 22; 8(1):12-5.
5) Wu Q, Luo Y, Lu R, Lau N, Lai EC, Li WX, Ding SW.Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1606-11.
6) Aliyari R#, Wu Q#, Li HW, Wang XH, Li F, Green LD, Han CS, Li WX, Ding SW.Mechanism of induction and suppression of antiviral immunity directed by virus-derived small RNAs in Drosophila. Cell Host Microbe. 2008 Oct 16; 4(4):387-97. (# Co-first author
7) Kim YC#, Wu Q# ,Chen J#, Xuan Z, Jung YC, Zhang MQ, Rowley JD, Wang SM. The transcriptome of human CD34+ hematopoietic stem-progenitor cells. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8278-83. (# Co-first author

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