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GAO Ping, Professor Bio-X Interdisciplinary Sciences
Name:  GAO Ping(高平)
Address: No. 443 Huangshan Rd, Hefei, Anhui, China, 230027
School of Life Science, University of Science & Technology of China
Tel: 86-551-63607033
Fax: 86-551-6360-7012
E-mail: pgao2@ustc.edu.cn
 
EDUCATION AND RESEARCH EXPERIENCE
1992年于军医进修学院(301医院)获医学硕士学位,2003年于日本大阪大学医学院获博士学位,2003至2005年在美国国立癌症研究所(NCI)从事博士后研究,曾于2005年获得NIH的杰出研究员奖(Fellow Award for Research Excellence)。2005年至2010年,在美国约翰霍普金斯大学医学院任博士后及助理研究员,曾获得约翰霍普金斯大学医学院2008年度的青年研究者奖 (Young Investigator Award)。在 Nature、Cancer Cell、Nature Communications、 Nature Review Cancer、Cell metabolism、EMBO J、PNAS、Blood 等杂志发表论文50多篇,论文他引累计在3000次以上。2010年12月起任中国科学技术大学生命科学学院教授,博士生导师。2013年1月入选安徽百人计划特聘教授。目前承担国家科技部973计划重大研究课题(首席科学家)、中科院先导项目、国家自然科学基金课题等。
 
RESEARCH INTERESTS
1) 肿瘤代谢调控的分子机制;
2) 非编码RNA对干细胞命运的调节作用。
 
REPRESENTATIVE PUBLICATIONS
1) Cao Y, GuoWT, TianS, HeX, Wang X, LiuXM, Gu K, MaX, Huang D, HuL, CaiYP, ZhangH, Wang YM*,Gao P*. miR-290/371-Mbd2-Myc Circuit Regulates Glycolytic Metabolism to Promote Pluripotency. EMBO J. (2015 In Press)
2) Ma X, Li C, Sun L, Huang D, Li T, He X, Wu G, Yang Z, Zhong X, Song L, Gao P*, Zhang H*. Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1. Nature Communications. 2014 ;5:5212.
3) Huang D, Li T, Li X, Zhang L, Sun L, He X, Zhong X, Jia D, Song L, Semenza GL, Gao P and Zhang H*. HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression. Cell Reports. 2014;8(6):1930-42.
4) He X, Cao Y, Wang L, Han Y, Zhong X, Zhou G, Cai Y, Zhang H, Gao P*. Human fibroblast reprogramming to pluripotent stem cells regulated by the miR19a/b-PTEN axis. PLos One. 2014; 9(4):e95213.
5) Gao P*, Sun L, He X, Cao Y, Zhang H. MicroRNAs and the Warburg Effect: new players in an old arena. Curr Gene Ther. 2012;12(4):285-91.
6) Gao P*. Chapter 20: MicroRNAs and Metabolism. In MicroRNAs in Cancer Translational Research, 1st Edition(William Cho Ed.) Springer New York. 2010.
7) Gao P*, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV*. c-myc suppression of mir-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature. 2009;458(7239):762-5.
8) Dang CV, Kim JW, Gao P, Yustein J. The interplay between MYC and HIF in cancer. Nature Review Cancer. 2008; 8(1): 51-6.
9) Dang CV*, Gao P. Muscle fatigue from losing your PHD. Cell Metabolism. 2008;7(3):191-2.
10) Gao P, Zhang H, Dinavahi R, Li F, Xiang Y, Raman V, Bhujwalla ZM, Felsher DW, Cheng L, Pevsner J, Lee LA, Semenza GL, Dang CV*. HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell. 2007;12(3):230-8.

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