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HU Bing, Professor Bio-X Interdisciplinary Sciences

Name:  Hu Bing (胡兵)
Born:   July 3, 1965, Hunan, P.R.China
Address: School of life science, University of Science and Technology of China, Hefei, Anhui 230027, P. R. China
Tel: 86-551-63602489
E-mail: bhu@ustc.edu.cn
Webpage: http://zebrafish.ustc.edu.cn
1984–1989 Bachelor of Biophysics, University of Science and Technology of China
1989–1992 Master of Biophysics, University of Science and Technology of China
1993–1998 Ph.D. of Neurobiology, University of Hong Kong and Institute of Physiology, Chinese Academy of Sciences, Shanghai, China (joint training)
1996–1999 Lecturer, Department of Neurobiology and Biophysics, USTC, China
2000.01–2001 Associate Professor, Department of Neurobiology and Biophysics, School of Life Sciences, USTC, China
2002–2004 Postdoctoral fellow, University of California at LA, CA,University of California at Irvine, CA
2005–2007.08 Senior RA, Research Officer, Department of Anatomy, Faculty of Medicine, University of Hong Kong, Hong Kong, China
2007.11–present Professor, Department of Neurobiology and Biophysics, School of Life Sciences, USTC, China
1) To study the oligodendrocyte development, myelin formation as well as remyelination after demyelination. Currently, we are focusing on elucidation of the mechanisms underlying zebrafish CNS remyelination after injury.
2) To study the synapse dynamic change using in vivo time-lapse confocal microscopy imaging in zebrafish and xenopus tadpoles.
1) Bing Hu, Henry K. Yip and Kwok-Fai So (1998) Localization of p75 neurotrophin receptor in the retina of the adult SD rat: An immunocytochemical study at light and electron microscopic levels. Glia 24:187-197.
2) Bing Hu, Henry K. Yip and Kwok-Fai So (1999) Expression of p75 neurotrophin receptor in the injured and regenerating rat retina. NeuroReport. 10:1293-1297.
3) Bing Hu, Xiangrui Li, Yifeng Zhou, Tiande Shou (2000) Effects of Bicuculline on Direction Sensitive Relay Cells in the Dorsal Lateral Geniculate Nucleus (LGNd) of Cats. Brain Research.885(1): 87-93.
4) Bing Hu, Angeliki Maria Nikolakopoulou and Susana Cohen-Cory (2005) BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo. Development. 132:4285-4298.
5) Sha Mi*, Bing Hu*, Kyungmin Hahm, Yi Luo, Edward Sai Kam Hui, Qiuju Yuan, Wai Man Wong, Li Wang, Huanxing Su, Tak-Ho Chu, Jiasong Guo, Wenming Zhang, Kwok-Fai So, Blake Pepinsky, Zhaohui Shao, Christilyn Graff, Ellen Garber, Vincent Jung, Ed Xuekui Wu & Wutian Wu* (2007) LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nature Medicine. 13(10):1228-1233. (* these authors contributed equally to this work). Cover page of the issue “the LINGO of remyelination”.
6) Ya-juan Li, Bing Hu* (2012) Establishment of multi-site infection model in zabrafish larvae for the study of Staphylococcus aureus infectious disease.Special Issue: zebrafish models. Journal of Genetics and Genomics. 39:521-534
7) Meng-Hua Xiong,†,‡ Ya-Juan Li,§,‡ Yan Bao,§ Xian-Zhu Yang,§ Bing Hu*,§ and Jun Wang*,§ (2012) Bacteria-Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery. Advanced Materials. 24, 6175–6180
8) Suqi Zou, Chen Tian, Shuchao Ge, Bing Hu* (2013) Neurogenesis of Retinal Ganglion Cells Is Not Essential to Visual Functional Recovery after Optic Nerve Injury in Adult Zebrafish. PLoS One. http://dx.plos.org/10.1371/journal.pone.0057280.
9) Yin, W., Hu, B*. (2014) Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish. Exp. Neurol. 251:72-83. http://dx.doi.org/10.1016/j.expneurol.2013.11.012
10) Chun-Rui Hu, Delong Zhang, Mikhail N. Slipchenko, Ji-Xin Cheng* Bing Hu*(2014)Label-free real-time imaging of myelination in the Xenopus laevis tadpole by in vivo stimulated Raman scattering microscopy. Journal of Biomedical Optics. 19(8), 086005. (Aug 07, 2014). http://dx.doi.org/10.1117/1.JBO.19.8.086005
11) Da-long Ren1, Ya-juan Li, Bing-bing Hu, Han Wang* ,  and Bing Hu* (2015)Melatonin regulates the rhythmic migration of neutrophils in live zebrafish. J Pineal Res., Doi:10.1111/jpi.12230.
12)  Da-Long Ren, Ai-Ai Sun, Ya-Juan Li, Min Chen, Shu-Chao Ge andBing Hu* (2015) Exogenous melatonin inhibits neutrophil migration through suppression of ERK activation. Journal of Endocrinology. 227 :49–60.
13) Tian C, Zou S, Hu B*(2016) Extraocular Source of Oligodendrocytes Contribute to Retinal Myelination and Optokinetic Responses in Zebrafish.Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2129-38. doi: 10.1167/iovs.15-17675. (highlight in the same issue)
14) Li Zhang, Yubin Huang & Bing Hu* (2016),Olfactory experiences dynamically regulate plasticity of dendritic spines in granule cells of Xenopus tadpoles in vivo. Scientific Reports 6:35009 Oct. DOI: 10.1038/srep35009.
15) Chen, M., Xu, Y., Huang, R., Huang Yubin, Ge Shuchao and Hu Bing* (2016) ,N-Cadherin is Involved in Neuronal Activity-Dependent Regulation of Myelinating Capacity of Zebrafish Individual Oligodendrocytes In Vivo. Molecular Neurobiology, (), 1-14. doi:10.1007/s12035-016-0233-4

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