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WANG Jun, Professor, Hundred Talents Program Bio-X Interdisciplinary Sciences

Name: Jun Wang(王均)
Address: Life Sciences Building, Room #215, School of Life Sciences, University of Science and Technology of China (USTC), Anhui, Hefei 230027, P. R. China
Tel: 86-551-63600335(O)
Fax: 86-551-63600402
E-mail: jwang699@ustc.edu.cn
Homepage: http://nanomedicine.ustc.edu.cn/yys_1/
 
EDUCATION AND RESEARCH EXPERIENCE
 1989–1993 B.Sc. in Chemistry and joint B.Sc. in Cell Biology, Wuhan University, Wuhan, China
 1993–1998 Ph.D. in Polymer Chemistry and Physics, degree conferred 1999, Wuhan University, Wuhan, China
 1999–2002 Postdoctoral Research Fellow in Tissue and Therapeutic Engineering Lab, Johns Hopkins Singapore, Singapore
 2002–2004 Postdoctoral Research Fellow, Johns Hopkins University School of Medicine, Department of Biomedical Engineering, Baltimore, USA
 2004–2006 Professor, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, China
 2005 Selected into "Hundred Talents Program" of the Chinese Academy of Sciences
 2006–present Professor, School of Life Sciences, University of Science and Technology of China, Hefei, China, and joint Professor of Hefei National Laboratory for Physical Sciences at Microscale
 
RESEARCH INTERESTS
We are attempting to develop nanomaterials-based delivery systems for targeted cancer therapy, mainly are focusing on RNAi-based cancer therapy , cancer stem cell targeted therapy and immunotherapy.
 
CURRENT RESEARCH PROJECTS 
1) The National Basic Research Program of China (973 Program 2015CB932100), 2015-2019
2) The National Natural Science Foundation of China (51390482),2014-2018
3) The National Natural Science Foundation for Distinguished Young Scholars of China (51125012), 2012-2015
 
REPRESENTATIVE PUBLICATIONS
1) Meng-Hua Xiong, Yan Bao, Xian-Zhu Yang, Yan-Hua Zhu, Jun Wang*, Delivery of Antibiotics with Polymeric Particles, Advanced Drug Delivery Reviews, 2014, 78, 63-76
2) Hong-Xia Wang#, Xian-Zhu Yang#, Chun-Yang Sun, Cheng-Qiong Mao, Yan-Hua Zhu, Jun Wang*, Matrix Metalloproteinase 2-Responsive Micelle for siRNA Delivery, Biomaterials, 2014, 35, 7622-7634
3) Jin-Zhi Du#, Cheng-Qiong Mao#, You-Yong Yuan, Xian-Zhu Yang, Jun Wang*, Tumor Extracellular Acidity-Activated Nanoparticles as Drug Delivery Systems for Enhanced Cancer Therapy, Biotechnology Advances, 2014, 32, 789-803 (invited review)
4) Xian-Zhu Yang#, Xiao-Jiao Du#, Yang Liu, Yan-Hua Zhu, Yang-Zhong Liu, Ya-Ping Li, Jun Wang*,Rational Design of Polyion Complex Nanoparticles to Overcome Cisplatin Resistance in Cancer Therapy, Advanced Materials, 2014, 26, 931-936
5) Tian-Meng Sun#, Yu-Cai Wang#, Feng Wang, Jin-Zhi Du, Cheng-Qiong Mao, Chun-Yang Sun, Rui-Zhi Tang, Yang Liu, Jing Zhu, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang*,Cancer Stem Cell Therapy Using Doxorubicin Conjugated to Gold Nanoparticles via Hydrazone Bonds, Biomaterials, 2014, 35, 836-845
6) Wen-Qing Li, Chun-Yang Sun, Feng Wang, Yu-Cai Wang, Yi-Wen Zhai, Meng Liang, Wen-Jing Liu, Zhi-Min Liu, Jun Wang*, Fei Sun*, Achieving a New Controllable Male Contraception by Photothermal Effect of Gold Nanorods, Nano Letters, 2013, 13, 2477-2484
7) Hong-Xia Wang, Meng-Hua Xiong, Yu-Cai Wang, Jing Zhu, Jun Wang*, N-Acetylgalactosamine Functionalized Mixed Micellar Nanoparticles for Targeted Delivery of siRNA to Liver,Journal of Controlled Release,2013, 166, 106-114
8) Meng-Hua Xiong, Ya-Juan Li, Yan Bao, Xian-Zhu Yang, Bing Hu*, Jun Wang*, Bacteria-Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery, Advanced Materials, 2012, 24, 6175-6180
9) You-Yong Yuan, Chen-Qiong Mao, Xiao-Jiao Du, Jin-Zhi Du, Feng Wang, Jun Wang*, Surface Charge Switchable Nanoparticles based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor, Advanced Materials, 2012, 24, 5476-5480
10) Yan-Dan Yao, Tian-Meng Sun, Song-Yin Huang, Shuang Dou, Ling Lin, Jia-Ning Chen, Jian-Bin Ruan, Cheng-Qiong Mao, Feng-Yan Yu, Mu-Sheng Zeng, Jian-Ye Zang, Qiang Liu, Feng-Xi Su, Peter Zhang, Judy Lieberman*, Jun Wang*, Erwei Song*, Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis, Science Translational Medicine, 2012, 4, 130ra48


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