|
EDUCATION AND RESEARCH EXPERIENCE
| 1989–1993 |
B.Sc. in Chemistry and joint B.Sc. in Cell Biology, Wuhan University, Wuhan, China |
| 1993–1998 |
Ph.D. in Polymer Chemistry and Physics, degree conferred 1999, Wuhan University, Wuhan, China |
| 1999–2002 |
Postdoctoral Research Fellow in Tissue and Therapeutic Engineering Lab, Johns Hopkins Singapore, Singapore |
| 2002–2004 |
Postdoctoral Research Fellow, Johns Hopkins University School of Medicine, Department of Biomedical Engineering, Baltimore, USA |
| 2004–2006 |
Professor, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, China |
| 2005 |
Selected into "Hundred Talents Program" of the Chinese Academy of Sciences |
| 2006–present |
Professor, School of Life Sciences, University of Science and Technology of China, Hefei, China, and joint Professor of Hefei National Laboratory for Physical Sciences at Microscale |
RESEARCH INTERESTS
We are attempting to develop nanomaterials-based delivery systems for targeted cancer therapy, mainly are focusing on RNAi-based cancer therapy and cancer stem cell targeted therapy by developing tumor microenviormental sensitive nanoparticular delivery systems.
CURRENT RESEARCH PROJECTS
| 1) |
The National Basic Research Program of China (973 Program 2010CB934001) |
| 2) |
The National Natural Science Foundation of China (20974105) |
| 3) |
The National Natural Science Foundation of China (50733003) |
| 4) |
The Fundamental Research Funds for the Central Universities (WK2070000008) |
REPRESENTATIVE PUBLICATIONS
| 1) |
Feng Wang, Yu-Cai Wang, Shuang Dou, Meng-Hua Xiong, Tian-Meng Sun, Jun Wang*, Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells, ACS Nano, 2011, 5, 3679-3692 |
| 2) |
Tian-Meng Sun, Jin-Zhi Du, Yan-Dan Yao, Cheng-Qiong Mao, Shuang Dou, Song-Yin Huang, Pei-Zhuo Zhang, Kam W. Leong, Er-Wei Song*, Jun Wang*, Simultaneous Delivery of siRNA and Paclitaxe via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression, ACS Nano, 2011, 5, 1483-1494 |
| 3) |
Cheng-Qiong Mao, Jin-Zhi Du, Tian-Meng Sun, Yan-Dan Yao, Pei-Zhuo Zhang, Er-Wei Song*, Jun Wang*, A Biodegradable Amphiphilic and Cationic Triblock Copolymer for the Delivery of siRNA Targeting the Acid Ceramidase Gene for Cancer Therapy, Biomaterials, 2011, 32, 3124-3133 |
| 4) |
Xi-Qiu Liu, Wen-Jing Song, Tian-Meng Sun, Pei-Zhuo Zhang, Jun Wang*, Targeted delivery of antisense inhibitor of miRNA for antiangiogenesis therapy using cRGD-functionalized nanoparticles, Molecular Pharmaceutics, 2011, 8, 250-259 (Most read articles in Jan and April 2011) |
| 5) |
Jin-Zhi Du, Tian-Meng Sun, Wen-Jing Song, Juan Wu, Jun Wang*, A Tumor-Acidity-Activated Charge-Conversional Nanogel as an Intelligent Vehicle for Promoted Tumoral-Cell Uptake and Drug Delivery, Angewandte Chemie-International Edition, 2010, 49, 3621-3626 |
| 6) |
Wen-Jing Song, Jin-Zhi Du, Tian-Meng Sun, Pei-Zhuo Zhang, Jun Wang*, Gold Nanoparticles Capped with Polyethylenimine for Enhanced siRNA Delivery, Small, 2010, 6, 239-246 |
| 7) |
Ling-Yan Tang, Yu-Cai Wang,* Yang Li, Jin-Zhi Du, Jun Wang*, Shell-Detachable Micelles Based on Disulfide-Linked Block Copolymer as Potential Carrier for Intracellular Drug Delivery, Bioconjugate Chemistry, 2009, 20, 1095-1099 (most-accessed article during April-June 2009) |
| 8) |
Tian-Meng Sun, Jin-Zhi Du, Li-Feng Yan, Hai-Quan Mao, Jun Wang*, Self-Assembled Biodegradable Micellar Nanoparticles of Amphiphilic and Cationic Block Copolymer for siRNA Delivery, Biomaterials, 2008, 29, 4348-4355 |
| 9) |
Zhen-Zhen Lu, Juan Wu, Tian-Meng Sun, Jing Ji, Li-Feng Yan, Jun Wang*, Biodegradable Polycation and Plasmid DNA Multilayer Film for Prolonged Gene Delivery to Mouse Osteoblasts, Biomaterials, 2008, 29, 733-741 |
| 10) |
Yu-Cai Wang, Xi-Qiu Liu, Tian-Meng Sun, Meng-Hua Xiong, Jun Wang*, Functionalized Micelles from Polyphosphoester and Poly(epsilon-caprolactone) Block Copolymer for Receptor-Mediated Drug Delivery, Journal of Controlled Release, 2008, 128, 32-40 | |
