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EDUCATION AND RESEARCH EXPERIENCE
| 1989–1993 |
B.Sc. in Chemistry and joint B.Sc. in Cell Biology, Wuhan University, Wuhan, China |
| 1993–1998 |
Ph.D. in Polymer Chemistry and Physics, degree conferred 1999, Wuhan University, Wuhan, China |
| 1999–2002 |
Postdoctoral Research Fellow in Tissue and Therapeutic Engineering Lab, Johns Hopkins Singapore, Singapore |
| 2002–2004 |
Postdoctoral Research Fellow, Johns Hopkins University School of Medicine, Department of Biomedical Engineering, Baltimore, USA |
| 2004–2006 |
Professor, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, China |
| 2005 |
Selected into "Hundred Talents Program" of the Chinese Academy of Sciences |
| 2006–present |
Professor, School of Life Sciences, University of Science and Technology of China, Hefei, China, and joint Professor of Hefei National Laboratory for Physical Sciences at Microscale |
RESEARCH INTERESTS
We are attempting to develop nanomaterials-based delivery systems for targeted cancer therapy, mainly are focusing on RNAi-based cancer therapy , cancer stem cell targeted therapy and immunotherapy.
CURRENT RESEARCH PROJECTS
| 1) |
The National Basic Research Program of China (973 Program 2015CB932100), 2015-2019 |
| 2) |
The National Natural Science Foundation of China (51390482),2014-2018 |
| 3) |
The National Natural Science Foundation for Distinguished Young Scholars of China (51125012), 2012-2015 |
REPRESENTATIVE PUBLICATIONS
| 1) |
Meng-Hua Xiong, Yan Bao, Xian-Zhu Yang, Yan-Hua Zhu, Jun Wang*, Delivery of Antibiotics with Polymeric Particles, Advanced Drug Delivery Reviews, 2014, 78, 63-76 |
| 2) |
Hong-Xia Wang#, Xian-Zhu Yang#, Chun-Yang Sun, Cheng-Qiong Mao, Yan-Hua Zhu, Jun Wang*, Matrix Metalloproteinase 2-Responsive Micelle for siRNA Delivery, Biomaterials, 2014, 35, 7622-7634 |
| 3) |
Jin-Zhi Du#, Cheng-Qiong Mao#, You-Yong Yuan, Xian-Zhu Yang, Jun Wang*, Tumor Extracellular Acidity-Activated Nanoparticles as Drug Delivery Systems for Enhanced Cancer Therapy, Biotechnology Advances, 2014, 32, 789-803 (invited review) |
| 4) |
Xian-Zhu Yang#, Xiao-Jiao Du#, Yang Liu, Yan-Hua Zhu, Yang-Zhong Liu, Ya-Ping Li, Jun Wang*,Rational Design of Polyion Complex Nanoparticles to Overcome Cisplatin Resistance in Cancer Therapy, Advanced Materials, 2014, 26, 931-936 |
| 5) |
Tian-Meng Sun#, Yu-Cai Wang#, Feng Wang, Jin-Zhi Du, Cheng-Qiong Mao, Chun-Yang Sun, Rui-Zhi Tang, Yang Liu, Jing Zhu, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang*,Cancer Stem Cell Therapy Using Doxorubicin Conjugated to Gold Nanoparticles via Hydrazone Bonds, Biomaterials, 2014, 35, 836-845 |
| 6) |
Wen-Qing Li, Chun-Yang Sun, Feng Wang, Yu-Cai Wang, Yi-Wen Zhai, Meng Liang, Wen-Jing Liu, Zhi-Min Liu, Jun Wang*, Fei Sun*, Achieving a New Controllable Male Contraception by Photothermal Effect of Gold Nanorods, Nano Letters, 2013, 13, 2477-2484 |
| 7) |
Hong-Xia Wang, Meng-Hua Xiong, Yu-Cai Wang, Jing Zhu, Jun Wang*, N-Acetylgalactosamine Functionalized Mixed Micellar Nanoparticles for Targeted Delivery of siRNA to Liver,Journal of Controlled Release,2013, 166, 106-114 |
| 8) |
Meng-Hua Xiong, Ya-Juan Li, Yan Bao, Xian-Zhu Yang, Bing Hu*, Jun Wang*, Bacteria-Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery, Advanced Materials, 2012, 24, 6175-6180 |
| 9) |
You-Yong Yuan, Chen-Qiong Mao, Xiao-Jiao Du, Jin-Zhi Du, Feng Wang, Jun Wang*, Surface Charge Switchable Nanoparticles based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor, Advanced Materials, 2012, 24, 5476-5480 |
| 10) |
Yan-Dan Yao, Tian-Meng Sun, Song-Yin Huang, Shuang Dou, Ling Lin, Jia-Ning Chen, Jian-Bin Ruan, Cheng-Qiong Mao, Feng-Yan Yu, Mu-Sheng Zeng, Jian-Ye Zang, Qiang Liu, Feng-Xi Su, Peter Zhang, Judy Lieberman*, Jun Wang*, Erwei Song*, Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis, Science Translational Medicine, 2012, 4, 130ra48 | |
