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BI Guoqiang, Professor, Changjiang-Professor, National Outstanding Youth, Hundred Talents Program Bio-X Interdisciplinary Sciences

Name:  Bi Guo-Qiang (毕国强)
Born:   November 1967, Hebei, P.R. China
Address: School of Life Sciences, University of Science and Technology of China, 230026 Hefei, P. R. China
Tel:

86-551-63602466

E-mail:  gqbi@ustc.edu.cn
 
EDUCATION AND RESEARCH EXPERIENCE
 1985-1989 B.S. (Physics), Beijing University, China
 1990-1991 M.S. (Physics), New York University, USA
 1991-1996 Ph.D. (Biophysics), University of California, Berkeley, USA
 1996-2000 Postdoctoral Fellow, University of California, San Diego, USA
 2000-2009 Assistant Professor, Associate Professor(with tenure), University of Pittsburgh School of Medicine, USA
 2007- Professor, University of Science and Technology of China
 2014- Senior Investigator, CAS Center for Excellence in Brain Research
 
RESEARCH INTERESTS
1) Synaptic structure and plasticity
2) Neural circuit structure and dynamics
3) Learning, memory and related brain diseases
4) Ultra-high resolution optical and electron imaging
 
CURRENT RESEARCH PROJECTS
1) National Outstanding Young Scientist Award, National Natural Science Foundation of China (2007-2011)
2) Dynamic Assembly of Protein Complex, Ministry of Science and Technology of China (2007-2012)
 
REPRESENTATIVE PUBLICATIONS
1) Shim SH, Xia C, Zhong G, Babcock HP, Vaughan JC, Huang B, Wang X, Xu C, Bi GQ* & Zhuang X*, Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. Proc Natl Acad Sci U S A 109: 13978-13983 (2012).
2) Zhang JC, Lau PM & Bi GQ*, Gain in sensitivity and loss in temporal contrast of STDP by dopaminergic modulation at hippocampal synapses. Proc Natl Acad Sci U S A 106: 13028-13033 (2009).
3) Lau, PM & Bi, GQ*, Synaptic mechanisms of persistent reverberatory activity in neuronal networks. Proc Natl Acad Sci U S A 102: 10333-10338 (2005).
4) Bi, GQ* & Rubin, J Timing in synaptic plasticity: from detection to integration. Trends Neurosci 28: 222-228 (2005).
5) Wang HX, Gerkin, RC, Nauen, DW & Bi, GQ*, Coactivation and timing-dependent integration of synaptic potentiation and depression. Nat Neurosci 8: 187-193 (2005).
6) Bi, GQ* & Poo, MM*, Synaptic modifications by correlated activity: Hebb's postulate revisited. Ann Rev Neurosci 24: 139-166 (2001).
7) Bi, GQ* & Poo, MM, Distributed synaptic modification in neural networks induced by patterned stimulation. Nature 401: 792-796 (1999).
8) Bi, GQ & Poo, MM, Synaptic modifications in cultured hippocampal neurons: Dependence on spike timing, synaptic strength, and postsynaptic cell type. J Neurosci 18: 10464-10472 (1998).
9) Steinhardt, RA, Bi, GQ & Alderton JM, Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release. Science 263: 390-393 (1994).

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