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SUN Fei, Professor Structure and Function of Biomacromolecules
Name:  Sun Fei (孙斐)
Born:   1971.11 Jiangsu
Address: School of Life Science, University of Science and Technology of China, Hefei, Anhui 230027, P. R. China
Tel: 81-551-63600864
Fax: 86-551-63602703
E-mail: feisun@ustc.edu.cn
 
   2000年毕业于复旦大学,获医学博士学位。2000-2002 年以色列Weizmann Institute of Science博士后;曾于2001年在阿根廷National University of Córdoba进行合作研究;2002年11-2006年8月加拿大University of Calgary博士后。工作以来作为第一或通讯作者共发表SCI研究论文34篇,被他人引用近500次;其中8篇论文分别被选做当期杂志的封面。
 
RESEARCH DIRECTION
生殖与生育的调节机制 

RESEARCH INTERESTS
1) 男性不育发生的分子遗传学机制和“分子标签”的筛选。
2) 非编码RNAs (如microRNAs, piRNAs, 长链非编码RNAs (lncRNAs), 内源性siRNAs等)调控哺乳动物精子和卵子发生的路径及与生育异常的关联。
3) 配子形成过程中减数分裂重组交换发生的分子调控机制。
 
CURRENT RESEARCH PROJECTS 
Project supported by the National Science Foundation for Distinguished Young Scholars of China; Project supported by the Major Science Research plan of National;   

REPRESENTATIVE PUBLICATIONS
1) Yao GD, Yin MM, Lian J, Tian H, Liu L, Li X,Sun F.MicroRNA-224 is involved in transforming growth factor-β-mediated mouse granulosa cel1 proliferation and granulosa cell function by targeting Smad4. MolEndocrinol,2010, 24(3): 540-551.
2) Liang N, Xu YL, Yin YM, Yao GD, Tian H, Wang GS, Lian J, Wang Y, and Sun F.Steroidogenic Factor-1 Is Required for TGF-β3-Mediated 17β-Estradiol Synthesis in Mouse Ovarian Granulosa Cells. Endocrinology,2011 Aug;152(8):3213-25.
3) Yin M, Lü M, Yao G, Tian H, Lian J, Liu L, Liang M, Wang Y, Sun F.Transactivation of microRNA-383 by Steroidogenic Factor-1 Promotes Estradiol Release from Mouse Ovarian Granulosa Cells by Targeting RBMS1.MolEndocrinol. 2012 Jul;26(7):1129-43.
4) Tian H, Cao YX, Zhang XS, Liao WP, Yi YH, Lian J, Liu L, Huang HL, Liu WJ, Yin MM, Liang M, Shan G, Sun F. The targeting and functions of miRNA-383 are mediated by FMRP during spermatogenesis.Cell Death Dis. 2013 May 2;4:e617.
5)  Li WQ, Sun C, Wang F, Wang YC, Zhai YW, Liang M, Liu WJ, Liu ZM, Wang J, Sun F. Achieving a new controllable male contraception by photothermal effect of gold nanorods. NanoLett 2013, 13 (6), 2477–2484.Comments on: Nature Matertials,2013,12 (7), 602: Nano contraception.


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