Name:Xuebiao Yao(X. Yao, 姚雪彪)
Address:Laboratory of Cellular Dynamics, University of Science and 

Technology of China, 230026 Hefei, P. R. China
Tel:86-551-63607141
Fax:86-551-63606304
E-mail:yaoxb@ustc.edu.cn
EDUCATION AND RESEARCH EXPERIENCE
1980-1984B.S., Jiangxi College of Chinese Medicine, China
1991-1995Ph.D., University of California-Berkeley, USA
1995-1997Research Associate, University of California-San Diego, USA
1997-1999Assistant Professor, University of Wisconsin-Madison, USA
2000-2003Visiting Research Professor, University of California-Berkeley, USA
2003-2008Georgia Cancer Coalition Eminent Scholar, USA
1999-Professor of Cell Biology, University of Science & Technology of China
2008-Director, Anhui Key Laboratory for Cellular Dynamics and Chemical Biology, China
RESEARCH INTERESTS
1.Chromosome segregation and stemness control
2.Organoids architect and plasticity control
3.Chemical biology of mitosis and metastasis
4.Single molecule and super-resolution imaging
CURRENT RESEARCH PROJECTS
1.Centromere Dynamics & Plasticity Control, Natural Science Foundation of China (2017-2012)
2.Chemical biology of mitosis, Chinese Academy of Sciences (2016-2020)
3.Single cell dynamics, Natural Science Foundation of China (2015-2019)
REPRESENTATIVE PUBLICATIONS
1.Ding X, Yan F, Yao P, Yang Z, Wan W, Wang X, Liu J, Gao X, Abrieu A, Zhu T, Zhang J, Dou Z, Yao X. (2010). Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin. Cell Res. 20, 1386-1389.
2.Chen Y, Wang D, Guo Z, Zhao J, Wu B, Deng H, Xiang H, Gao F, Yu X, Liao J, Ward T, Xia P, Emenari C. Ding X, Thompson W, Ma K, Zhu J, Aikhionbare F, Dou K, Zhu J, Cheng S, and Yao X. 2011. Rho kinase phosphorylation promotes ezrin-mediated metastasis in hepatocellular carcinoma. Cancer Research 71, 1721-1730.
3.Chen J, Yu F, Gong C, Yao D, Deng H, Wang F, Anderson K, Liu Q, McEwen M, Yao X*, Song E*. 2011. CCL18 from tumor associated macrophages promotes breast cancer metastasis via PITPNM3. Cancer Cell 19, 541-555; *correspondence.
4.Tao Y, Jin C, Li X, Qi S, Chu L, Niu L, Yao X*, Teng M*. 2012. The structure of the FANCM-MHF complex reveals physical features for functional assembly. Nature Commun. 3, 782-791.
5.Xia P, Wang Z, Liu X, Wu B, Wang J, Ward T, Zhang L, Ding X, Gibbons G, Shi Y, Yao X. (2012). EB1 acetylation by PCAF ensures accurate kinetochore-microtubule interactions in mitosis. Proc Natl Acad Sci U S A. 109, 16564-9.
6.Zhao X, Wang D, Liu X, Liu L, Song Z, Zhu T, Adams G, Gao X, Tian R, Huang Y, Chen R, Wang F, Teng M, Ding X, Yao X. (2013) Phosphorylation of the BAR domain of ACAP4 regulates membrane tabulation. Proc Natl Acad Sci U S A. 110, 11023-8.
7.Yao X, Li D, Pei G. 2013. In focus: Molecular and Cell Biology Research in China. Nat Rev Mol Cell Biol. 14, 600-606.
8.Dou Z, Liu X, Wang W, Zhu T, Wang X, Xu L, Abrieu A, Fu C, Hill DL, Yao X*. 2015. Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment. Proc Natl Acad Sci USA. 112, E4546-55.
9.Mo F, Zhuang X, Liu X*, Yao P, Qin B, Su Z, Zang J, Wang Z, Zhang J, Niu L, Hill DL, Fang G, Fu C, Yao X*. 2016. Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation. Nature Chem. Biol. 12, 226-232.  *correspondence.

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